METHOTREXATE TREATMENT SUPPRESSES MONOCYTES IN NONRESPONDERS TO PNEUMOCOCCAL CONJUGATE VACCINE IN RHEUMATOID ARTHRITIS PATIENTS

Methotrexate Treatment Suppresses Monocytes in Nonresponders to Pneumococcal Conjugate Vaccine in Rheumatoid Arthritis Patients

Patients with rheumatoid arthritis (RA) have an increased risk of infections; therefore, immunization against vaccine-preventable diseases is important.Methotrexate (MTX) impairs the antibody response to pneumococcal conjugate vaccine (PCV) in patients with arthritis, and the underlying mechanism is largely THYRO SUPPORT unknown.Here, we investigat

read more

Operationalizing intimacy and identity aspects of personality functioning in relation to personality disorder in adolescents

According to dimensional models of personality pathology, deficits in interpersonal (intimacy and empathy) and self (identity and self-direction) function (Criterion A) are core to all personality disorders.These aspects of personality functioning (Criterion A) have seldom been evaluated for how they might relate to one another in the context of pe

read more


Membrane fouling and control in algae-rich water treatment

Microfiltration Wedge and ultrafiltration membrane technology has now become one of the important methods for algae-rich water treatment due to its better solid-liquid separation effect and microbial retention capacity, while the existence of membrane fouling has been restricting the full-scale promotion and application of low-pressure membrane tec

read more

Midgut Mitochondrial Function as a Gatekeeper for Malaria Parasite Infection and Development in the Mosquito Host

Across diverse organisms, various physiologies are profoundly regulated by mitochondrial function, which is defined by mitochondrial fusion, biogenesis, oxidative Peanuts phosphorylation (OXPHOS), and mitophagy.Based on our data and significant published studies from Caenorhabditis elegans, Drosophila melanogaster and mammals, we propose that midgu

read more